Dr. Brown has over 15 years of experience studying the reward system. His laboratory is primarily interested in understanding the neurobiological mechanisms of drug addiction and obesity. Specifically, Dr. Brown’s lab is interested in how regulation of the extracellular matrix mediates synaptic organization and behavioral output. His laboratory uses a multifaceted approach combining rodent behavior, electrophysiology, and molecular techniques, with the hope that targeting molecules that influence the extracellular matrix may provide novel therapeutics for the treatment of drug addiction and obesity.
A second line of research in the lab is studying the role of peptidases in nociceptive signaling. The goal of this research is to develop novel analgesics to not only alleviate the symptoms of pain but target the pathological etiology.
Dr. Brown obtained his Ph.D. from Washington State University in 2008 under the mentorship of Dr. Barbara Sorg. Upon completion of his Ph.D., Dr. Brown worked as a Postdoctoral Associate in Dr. Yan Dong’s laboratory at Washington State University. In 2009, Dr. Brown joined Dr. Julie Kauer’s laboratory at Brown University in Providence, Rhode Island, where he studied synaptic plasticity within the hippocampus and spinal cord. In 2012, Dr. Brown took a position as an Assistant Professor at The University of Wyoming in The School of Pharmacy. In 2018 Dr. Brown was promoted to Associate Professor with tenure in concurrence with becoming the Department Chair of Pharmaceutical Sciences within The School of Pharmacy. In 2021 Dr. Brown joined the Integrative Physiology and Neuroscience Department at Washington State University as an Associate Professor.
NIH: Inhibitory Synaptic Transmission, Stress, and Drugs of Abuse (Co-I)
NIH: Perineuronal Nets and Cocaine Associated Memories (Co-PI)