Room: Veterinary and Biomedical Research Building (VBR) room 115
2014-Present Assistant Professor, IPN, Washington State University, Pullman, WA
In recent years it has become clear that feeding peptides, which fluctuate as a function of metabolic status, act in brain reward regions to regulate feeding and addictive behavior. Research in the Davis lab is focused on detailing the impact of feeding peptides on cellular, neurochemical and behavioral processes that contribute to addictive behavior(s). In general work from our lab has demonstrated that feeding peptides that stimulate food intake augment the motivation to obtain palatable food and drugs while those that attenuate feeding decrease these parameters. Feeding peptides achieve this regulation through action in brain reward circuits. Current projects are focused on detailing the ability of binge feeding behavior or bypass surgery, and subsequent changes in feeding peptides, to impact attention and motivation for palatable food and drugs of abuse.
Jon Davis, Assistant Professor in IPN, received his B.S. in Biology from Maryville College, Maryville, Tennessee in 1997. He then received a PhD in 2005 from the University of Cincinnati College of Medicine, Department of Cell Biology & Anatomy, Cincinnati, Ohio. From 2005-2010 he did postdoctoral work at the University of Cincinnati within the obesity research center. He then went on to become a research scientist within the Department of Psychiatry & Behavioral Neuroscience at University of Cincinnati. In 2014, he was appointed to the faculty as an Assistant Professor at Washington State University, Pullman, WA.
- Brutman JN, Sirohi S, Davis JF. (2019) Recent Advances in the Neurobiology of Altered Motivation Following Bariatric Surgery. Curr Psychiatry Rep. 21(11):117. PMID: 31707546 PMCID:
- Brutman JN, Zhang S, Choi P, Zhang Y, Stotts MJ, Michal J, Jiang Z, Davis JF. (2019) Vapor Cannabis Exposure Promotes Genetic Plasticity in the Rat Hypothalamus. Sci Rep. 9(1):16866 PMID: 31728018 PMCID: PMC6856070
- Brutman JN, Zhou X, Zhang Y, Michal J, Stark B, Jiang Z, Davis JF. (2018) Mapping diet-induced alternative polyadenylation of hypothalamic transcripts in the obese rat Physiol Behav. 188:173-180. doi: 10.1016/j.physbeh.2018.01.026. Epub 2018 Jan 31. PMID: 29391168 PMCID:
- Villavasso S, Shaw C, Skripnikova E, Shah K, Davis JF, Sirohi S. (2019) Nutritional Contingency Reduces Alcohol Drinking by Altering Central Neurotransmitter Receptor Gene Expression in Rats. Nutrients. 11(11). PMID: 31717954 PMCID: PMC6893745
- Brutman JN, Sirohi S, Davis JF. (2019) Examining the Impact of Estrogen on Binge Feeding, Food-Motivated Behavior, and Body Weight in Female Rats Obesity 1617-1626 PMID: 31411378 PMCID: https://doi.org/10.1002/oby.22582
- Sirohi S, Skripnikova E, Davis JF. (2019) Vertical Sleeve Gastrectomy Attenuates Hedonic Feeding Without Impacting Alcohol Drinking in Rats Obesity (4):603-611 PMID: 30740914 PMCID: PMC6430654 https://doi.org/10.1002/oby.22415
- Zhang S, Zhang Y, Zhou X, Fu X, Michal JJ, Ji G, Du M, Davis JF, Jiang Z. (2018) Alternative polyadenylation drives genome-to-phenome information detours in the AMPKα1 and AMPKα2 knockout mice. Sci Rep. 8(1):6462 PMID: 29691479 PMCID: PMC5915415
- Zhou X, Zhang Y, Michal JJ, Qu L, Zhang S, Wildung MR, Du W, Pouchnik DJ, Zhao H, Xia Y, Shi H, Ji G, Davis JF, Smith GD, Griswold MD, Harland RM, Jiang Z. (2019) Alternative polyadenylation coordinates embryonic development, sexual dimorphism and longitudinal growth in Xenopus tropicalis. Cell Mol Life Sci. 76(11):2185-2198 PMID: 30729254 PMCID: PMC6597005