Sensory Neuroscience and Pain
zebrafish

Sensory Neuroscience and Pain

The study of the molecular, cellular, and circuit basis of how the nervous system collects and integrates information about the external and internal environments. Particular focus is placed on understanding how these systems can be damaged (e.g., hearing loss and blindness), the neural underpinnings of acute and chronic pain, and the monitoring/control of organ systems (viscerosensation) in health and disease.

Recent research

  1. Dhakal S, Stevens CB, Sebbagh M, Weiss O, Frey RA, Adamson S, Shelden EA, Inbal A, Stenkamp DL (2015). Abnormal retinal development in cloche mutant zebrafish. Developmental Dynamics 244(11):1439-55. PMCID: PMC4619121 [Available on 2016-11-01]
  2. Sherpa T, Lankford T, McGinn T, Hunter SS, Frey RA, Ryan, M, Sun C, Robison BD, Stenkamp DL (2014). Retinal regeneration is facilitated by the presence of surviving neurons. Developmental Neurobiology 74(9):851-876. PMCID: PMC4106997
  3. Matthew Kruger, Robert Boney, Alexander J. Ordoobadi, Thomas F. Sommers, Josef G. Trapani and Allison B. Coffin (2016). Natural Bizbenzoquinoline Derivatives Protect Zebrafish Lateral Line Sensory Hair Cells from Aminoglycoside Toxicity. Front. Cell. Neurosci. http://dx.doi.org/10.3389/fncel.2016.00083 PMCID: PMC4811916
  4. Wakley AA, Wiley JL, Craft RM (2014). Sex differences in antinociceptive tolerance to THC. Drug Alcohol Depend 143:22-28. PMCID: PMC4161674
  5. Joanna F. Mulvaney, Cathrine Thompkins, Teppei Noda, Koji Nishimura, Willy W. Sun, Shuh-Yow Lin, Allison Coffin & Alain Dabdoub (2016). Kremen1 regulates mechanosensory hair cell development in the mammalian cochlea and the zebrafish lateral line. Scientific Reports 6, Article number: 31668 doi:10.1038/srep31668.  PMCID: PMC4994024

Research at Legacy

Legacy Research Institute is the research arm of Legacy Health, a private, non-profit health care provider in the city of Portland. Researchers at Legacy have several focuses including a cluster addressing diseases of the eye. Doctoral students in the Neuroscience Program may also undertake research in these labs.

Recent research at Legacy

  1. Ratcliff R, Van Dongen HP (2011). Diffusion model for one-choice reaction-time tasks and the cognitive effects of sleep deprivation. Proc Natl Acad Sci U S A. 108(27):11285-90. doi: 10.1073/pnas.1100483108. Epub 2011 Jun 20. PMCID: PMC3131321
  2. Boison D, and Aronica E (2015) Comorbidities in Neurology: Is Adenosine the Common Link? Neuropharmacology 97:18-34. PMCID: PMC4537378

Faculty working in this area

Meighan, Pete

Clinical Assistant Professor
pcm@vetmed.wsu.edu
 

Faculty at Legacy

Demirel, Shaban

Adjunct Associate Professor
sdemirel@deverseye.org

Fortune, Brad

Adjunct Associate Professor
bfortune@deverseye.org

Shen, Haiying

Senior Research Associate
hshen@downeurobiology.org