faculty

Yuanyuan Cui

Yuanyuan Cui

Research Assistant Professor

cuiyuanyuan@vetmed.wsu.edu

Office
Room: VBR 431
Phone: 335-7645

 

Education

2007 M.D. Basic Medicine; Peking University, Beijing
2010 Ph.D. Neuroscience; Neuroscience Research Institute; Peking University, Beijing

Prior Academic Appointments

2010-2012 Postdoctoral Fellow, Department of Biomedical Engineering, University of California, Davis
2013-2016 Postdoctoral Fellow, Department of Urology, University of California, Davis

Research

Yuanyuan Cui's research focuses on a series of topics in neurophysiology and cancer biology. She conducts translational research from understanding the fundamental physiological phenomena, solving pathological problems to aiding clinical therapy. More specifically, her research interests include:
1. Temperature and pain sensing mechanisms for TRP channels;
2. Castration resistant prostate cancer progression, drug resistance and nanostructured medicine for drug delivery;
3. Thermodynamics of biological processes.
 

Select Publications

  • J. Zhang, X. Luo, H. Li, X. Yue, L. Deng, Y. Cui*, Y. Lu.* (2014) MiR-223 functions as an oncogene in human colorectal cancer cells Oncol Rep 2(1):115-20. doi: 10.3892/or.2014.3173. Epub 2014 May 8. PMID: 24819398
  • Zhu Y, Liu C, Cui Y, Nadiminty N, Lou W, Gao AC. (2014) Interleukin-6 induces neuroendocrine differentiation (NED) through suppression of RE-1 silencing transcription factor (REST). Prostate 74(11):1086-94. doi: 10.1002/pros.22819. Epub 2014 May 12. PMID: 24819501
  • Cui Y, Nadiminty N, Liu C, Lou W, Schwartz CT, Gao AC. (2014) Upregulation of glucose metabolism by NF-κB2/p52 mediates enzalutamide resistance in castration-resistant prostate cancer cells. Endocr Relat Cancer 21(3):435-42. doi: 10.1530/ERC-14-0107. Print 2014 Jun. PMID: 24659479 PMCID: PMC4021715
  • Cui Y, Yamada S. (2013) N-cadherin dependent collective cell invasion of prostate cancer cells is regulated by the N-terminus of α-catenin. PLoS One. 8(1):e55069. doi: 10.1371/journal.pone.0055069. Epub 2013 Jan 24. PMID: 23359820 PMCID: PMC3554680
  • Cui Y, Yang F, Cao X, Yarov-Yarovoy V, Wang K, Zheng J. (2012) Selective disruption of high sensitivity heat activation but not capsaicin activation of TRPV1 channels by pore turret mutations. J Gen Physiol. 139(4):273-83. doi: 10.1085/jgp.201110724. Epub 2012 Mar 12. PMID: 22412190 PMCID: PMC3315147
  • Yang F, Cui Y, Wang K, Zheng J. (2010) Thermosensitive TRP channel pore turret is part of the temperature activation pathway. Proc Natl Acad Sci U S A. 107(15):7083-8. doi: 10.1073/pnas.1000357107. Epub 2010 Mar 29. PMID: 20351268 PMCID: PMC2872446