Room: Veterinary and Biomedical Research Building (VBR) room 115
2014-Present Assistant Professor, IPN, Washington State University, Pullman, WA
In recent years it has become clear that feeding peptides, which fluctuate as a function of metabolic status, act in brain reward regions to regulate feeding and addictive behavior. Research in the Davis lab is focused on detailing the impact of feeding peptides on cellular, neurochemical and behavioral processes that contribute to addictive behavior(s). In general work from our lab has demonstrated that feeding peptides that stimulate food intake augment the motivation to obtain palatable food and drugs while those that attenuate feeding decrease these parameters. Feeding peptides achieve this regulation through action in brain reward circuits. Current projects are focused on detailing the ability of binge feeding behavior or bypass surgery, and subsequent changes in feeding peptides, to impact attention and motivation for palatable food and drugs of abuse.
Jon Davis, Assistant Professor in IPN, received his B.S. in Biology from Maryville College, Maryville, Tennessee in 1997. He then received a PhD in 2005 from the University of Cincinnati College of Medicine, Department of Cell Biology & Anatomy, Cincinnati, Ohio. From 2005-2010 he did postdoctoral work at the University of Cincinnati within the obesity research center. He then went on to become a research scientist within the Department of Psychiatry & Behavioral Neuroscience at University of Cincinnati. In 2014, he was appointed to the faculty as an Assistant Professor at Washington State University, Pullman, WA.
|WSU/CVM Research Grant||Bariatric regulation of amphetamine reward||PI|
- Sirohi S, VanCleef A, Davis J (2016) Binge-like intake of HFD attenuates alcohol intake in rats. Physiol Behav. PMID: 27765644
- Terrill S, Hyde K, Kay K, Greene H, Maske C, Knierim A, Davis J, Williams D (2016) Ventral Tegmental Area orexin 1 receptors promote palatable food intake and oppose post-ingestive negative feedback Am J Physiol
- Sirohi S, Shurdak J, Seeley R, Benoit S, Davis J (2016) Central & peripheral glucagon-like peptide-1 receptor signaling differentially regulate addictive behaviors Physiol Behav 1(161), 140–144 PMID: 27072507
- Obici S, Magrisso IJ, Ghazarian AS, Shirazian A, Miller JR, Loyd CM, Begg DP, Krawczewski Carhuatanta KA, Haas MK, Davis JF, Woods SC, Sandoval DA, Seeley RJ, Goodyear LJ, Pothos EN, Mul JD (2015) Moderate voluntary exercise attenuates the metabolic syndrome in melanocortin-4 receptor-deficient rats showing central dopaminergic dysregulation Mol Metab 4(10), 692-705 PMID: 26500841 PMCID: PMC4588435
- Davis J, Shurdak J, Magrisso J, Seeley R, Benoit S (2013) Gastric Bypass Surgery Augments Ethanol Intake in the Rat Obesity Surgery 23 (7), 920-30
- Figlewicz D, Jay J, Acheson M, Magrisso I, West C, Zavosh A, Benoit S, Davis J (2013) Moderate High Fat Diet Increases Sucrose Self-Administration in Young Rats Appetite 61(1), 19-29 PMID: 23023044 PMCID: PMC3538965
- Davis J, Choi D, Pfluger P, Kirchner H, Zigman J, Tschop M, Benoit S (2012) GOAT Induced Ghrelin Acylation Regulates Hedonic Feeding Hormones & Behavior 62(5), 598-604 PMID: 22982020 PMCID: PMC3489978
- Davis J, Shurdak J, Magrisso J, Mul J, Grayson B, Pfluger P, Tschop M, Seeley R, Benoit S (2012) Gastric Bypass Surgery Attenuates Ethanol Consumption in Ethanol Preferring (P) Rats Biological Psychiatry 72(5), 354-60 PMID: 22444202
- Choi D, Davis J, Fitzgerald M, Benoit S (2012) Orexin Signaling in the Paraventricular Thalamus Regulates Hedonic Feeding in the Rat Neuroscience (210), 243-8 PMID: 22433299 PMCID: PMC3791334
- Davis J, Choi D, Clegg D, Benoit S (2011) Signaling Through the Ghrelin Receptor Modulates Hippocampal Function and Meal Anticipation in Mice Physiology & Behavior 103(1), 39-43 PMID: 21036184 PMCID: PMC3041863