Jon Davis, Ph.D.

Jon Davis, Ph.D.

 

 


Assistant Professor 
Office: Veterinary and Biomedical Research Building (VBR) room 115 
E-Mail: davisjo@vetmed.wsu.edu
Phone: (509) 335-8163



Recruiting Ph.D. students for fall 2017


Jon Davis Web Picture

Current Position

2014-Present Assistant Professor, IPN, Washington State University, Pullman, WA

Education

BA Biology, Maryville College
Ph.D. Cell Biology, University of Cincinnati


Biographical Information

Jon Davis, Assistant Professor in IPN, received his B.S. in Biology from Maryville College, Maryville, Tennessee in 1997. He then received a PhD in 2005 from the University of Cincinnati College of Medicine, Department of Cell Biology & Anatomy, Cincinnati, Ohio. From 2005-2010 he did postdoctoral work at the University of Cincinnati within the obesity research center. He then went on to become a research scientist within the Department of Psychiatry & Behavioral Neuroscience at University of Cincinnati. In 2014, he was appointed to the faculty as an Assistant Professor at Washington State University, Pullman, WA.


Research

In recent years it has become clear that feeding peptides, produced by the gastrointestinal tract, and which fluctuate as a function of metabolic status, act in the brain to regulate feeding and addictive behavior. Research in the Davis lab is focused on detailing the impact of feeding peptides on cellular, neurochemical and behavioral processes that contribute to addictive behavior(s). In general work from our lab has demonstrated that feeding peptides that stimulate food intake augment the motivation to obtain palatable food and drugs while those that attenuate feeding decrease these parameters. Feeding peptides achieve this regulation through action in brain reward circuits. Current projects are focused on detailing the ability of feeding peptides to control binge feeding behavior and new onset alcohol misuse following bypass surgery.


Current Funding

Alcohol and Drug Abuse Research Program (ADARP); Orexinergic Regulation of Binge Feeding in Rats. This project investigates the contribution of lateral hypothalamic orexin signaling for the control of binge feeding behavior in rodents. Role: PI


Publications

  1. Sirohi S, VanCleef A, Davis J. (2016) “Binge-like intake of HFD attenuates alcohol intake in rats.” 2016 Physiology & Behavior, epub ahead of print.
  2. Terrill S, Hyde K, Kay K, Greene H, Maske C, Knierim A, Davis J, Williams D (2016). “Ventral Tegmental Area orexin 1 receptors promote palatable food intake and oppose post-ingestive negative feedback.” Am J Physiol, Regulatory, Integrative and Comparative Physiology, epub ahead of print.
  3. Sirohi S, Shurdak J, Seeley R, Benoit S, Davis J. (2016) “Central & peripheral glucagon-like peptide-1 receptor signaling differentially regulate addictive behaviors.” 2016 Physiology & Behavior, 1(161), 140–144.
  4. Obici, S., Magrisso, I. J., Ghazarian, A. S., Shirazian, A., Miller, J. R., Loyd, C, Begg D, Krawczewski K, Haas M, Davis J, Woods S, Sandoval D, Seeley R, Goodyear L, Pothos M, Mul, J. D. (2015). “Moderate voluntary exercise attenuates the metabolic syndrome in melanocortin-4 receptor-deficient rats showing central dopaminergic dysregulation.” 2015 Molecular Metabolism, 4(10), 692–705.
  5. Davis J, Shurdak J, Magrisso J, Seeley R, Benoit S. “Gastric Bypass Surgery Augments Ethanol Intake in the Rat.” 2013 Obesity Surgery, 23 (7): 920-30.
  6. Figlewicz D, Jay J, Acheson M, Magrisso I, West C, Zavosh A, Benoit S, Davis J. “Moderate High Fat Diet Increases Sucrose Self-Administration in Young Rats.” 2012 Appetite, 61(1): 19-29.
  7. Davis J, Choi D, Pfluger P, Kirchner H, Zigman J, Tschop M, Benoit S. “GOAT Induced Ghrelin Acylation Regulates Hedonic Feeding.” 2012 Hormones & Behavior, 62(5):598-604.
  8. Davis J, Shurdak J, Magrisso J, Mul J, Grayson B, Pfluger P, Tschop M, Seeley R, Benoit S. “Gastric Bypass Surgery Attenuates Ethanol Consumption in Ethanol Preferring (P) Rats.” 2012 Biological Psychiatry, 72(5) 354-60.
  9. Choi D, Davis J, Fitzgerald M, Benoit S. “Orexin Signaling in the Paraventricular Thalamus Regulates Hedonic Feeding in the Rat.” 2012 Neuroscience, May 17 (210) 243-8.
  10. Davis J, Choi D, Clegg D, Benoit S.  “Signaling Through the Ghrelin Receptor Modulates Hippocampal Function and Meal Anticipation in Mice.”  2011 Physiology & Behavior, 103(1) 39-43.